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Omisore,N.O.A.; Adewunmi,C.O.; Iwalewa,E.O.; Ngadjui,B.T.; Adenowo,T.K.; Abegaz,B.M.; Ojewole,J.A.; Watchueng,J.. |
Dorstenia barteri and D. convexa extracts and some isolated components of the former were investigated for effectiveness against Trichomonas gallinarum and compared with quercetin and quercitrin. The antioxidant activity of the extracts/compounds was also determined. The minimum lethal concentrations (MLCs) for the extract of D. barteri leaves and twigs at 24 h were found to be 15.625 and 15.625 µg/ml, respectively. However, the MLCs of the leaf and twig extract of D. convexa were 125 and 437.5 µg/ml, respectively. The prenylated and geranylated chalcones were as active as the prenylated flavones, 6-prenylapigenin and the diprenylated derivative 6,8-diprenyleridictyol. The order of the antitrichomonal activity of the compounds at 24 h was: quercetin (0.121... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Dorstenia species; Antitrichomonal; Antioxidant activity; Prenylated flavonoids. |
Ano: 2005 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000700012 |
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